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Ketamine News and Research
Coverage in popular media
Ketamine in popular news media
Yale Medicine Video: Ketamine and Depression:How it works
Yale Medicine: How Ketamine Drug Helps with Depression
The Washington Post: Ketamine for Depression: What it Feels Like and Who it Can Help
The New Yorker: Ketamine Therapy Is Going Mainstream. Are We Ready?
Elemental: Ketamine Is Revealing a New Understanding of Depression and the Brain
Psychology Today: IV Ketamine for Treatment-Resistant Depression
Gizmodo: More Than Just a Trip: Why Does Ketamine Work for Depression When Nothing Else Does?
The New York Times: I Was Paralyzed by Severe Depression. Then Came Ketamine.
Societal consensus statements
2022 Updated US Guidelines for Treating MDD, Annals of Internal Medicine 2022
Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation, The American Journal of Psychiatry 2021
A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders, JAMA Psychiatry 2017
Intravenous Ketamine for Adults With Treatment-Resistant Depression or Post-Traumatic Stress Disorder: A Review of Clinical Effectiveness, Cost-Effectiveness and Guidelines, The Canadian Journal of Psychiatry 2021
Ketamine infusion therapy and depression (Systematic Reviews and Meta-Analyses)
Real-world effectiveness of ketamine in treatment-resistant depression: A systematic review & meta-analysis, Journal of Psychiatric Research 2022
Efficacy of ketamine for major depressive episodes at 2, 4, and 6-weeks post-treatment: A meta-analysis, Psychopharmacology 2021
Neurocognitive effects of ketamine and esketamine for Treatment-Resistant Major Depressive Disorder: A systematic review, Harvard Review of Psychiatry 2021
Comparative efficacy of racemic ketamine and esketamine for depression: A systematic review and meta-analysis, Journal of Affective Disorders 2021
Registered clinical trials investigating ketamine for psychiatric disorders, Journal of Psychiatric Research 2020
The relationship between subjective effects induced by a single dose of ketamine and treatment response in patients with Major Depressive Disorder: A systematic review, Journal of Affect Disorders 2020
Leveraging neuroplasticity to enhance adaptive learning: The potential for synergistic somatic-behavioral treatment combinations to improve clinical outcomes in Depression, Biological Psychiatry 2019
Ketamine therapy and depression
Cognitive Behavioral Therapy to Sustain the Antidepressant Effects of Ketamine in Treatment-Resistant Depression: A Randomized Clinical Trial, Psychotherapy and Psychosomatics 2021
Early symptomatic improvements as a predictor of response to repeated-dose intravenous ketamine, Progress in Neuro-Psychopharmacology and Biological Psychiatry 2021
Cardiovascular effects of repeated subanaesthetic ketamine infusion in depression, Journal of Psychopharmacology 2020
Antidepressant and Neurocognitive Effects of Serial Ketamine Administration Versus ECT in Depressed Patients, Journal of Psychiatric Research 2020
Ketamine Normalizes Subgenual Cingulate Cortex Hyper-Activity in Depression, Neuropsychopharmacology 2020
Maintenance Ketamine Therapy for Treatment-Resistant Depression, Journal of Clinical Psychopharmacology 2018
Depression and antidepressants
Ketamine drug properties and history
Ketamine Manufacturer Data Sheet, Pfizer
Ketamine - 50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms, Pharmacological Reports
Ketamine other uses
Bipolar Disorder: Ketamine for bipolar depression: a systematic review, International Journal of Neuropsychopharmacology 2021
Substance Abuse Disorder: Efficacy of Ketamine in the Treatment of Substance Use Disorders: A Systematic Review, Frontiers in Psychiatry 2018
Journal of Cerebral Blood Flow & Metabolism, 2022
Suicidal Thoughts: Ketamine for suicidal ideation in adults with psychiatric disorders: A systemic review and meta-analysis of treatment trials Au and Nz Journal of Psychiatry 2019
Anxiety Disorder: Efficacy and safety of ketamine in the management of anxiety and anxiety spectrum disorders: a review of the literature, CNS Spectrums 2019
Pain disorders: Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management, Regional Anesthesia and Pain Medicine 2018