The Question in the Room
The patient across from me is successful by every conventional measure: thriving business, loving family, objectively good life. She’s also been depressed for three years. We’ve tried two SSRIs, therapy, lifestyle interventions through our six-pillar program at MindWell. She’s optimized her sleep, cleaned up her diet, and exercises regularly. She’s done everything right. And she’s still struggling. This is not uncommon.
“What about ketamine?” she asks. “Or psilocybin? I keep reading about them. My therapist sent me an article from The New York Times about how they’re curing treatment-resistant depression.”
I pause, because this is the conversation that happens weekly now, sometimes daily. Five years ago, it was rare. Now it’s routine. Patients arrive with podcast episodes saved, studies their friends forwarded, and questions about flying to Oregon for legal psilocybin sessions or whether they should try ayahuasca in Costa Rica.
The honest answer is complex. Yes, …
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